Bioactive Small Molecules
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Filtered Search Results
Cayman Chemical HValProProOHtrIfluoroac 5mg
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A peptide ACE inhibitor (IC50 = 9 µM); inhibits acetylcholine-induced NO production in HUVECs at 1 µM; induces vasorelaxation in precontracted isolated rat aortic rings; decreases systolic blood pressure in spontaneously hypertensive rats at 0.3 mg/kg; dietary administration reduces plasma levels of total cholesterol, HDL-cholesterol, and triglycerides, expression of Il6 and Il1b, and aortic arch intimal thickening and atherosclerotic plaque formation in ApoE-/- mice
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Cayman Chemical ANTIBODY CBGAQ 5mg
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An analytical reference standard categorized as an oxidative quinone product of CBGA; intended for research and forensic applications
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Medchemexpress LLC 2-(DiMethylphosphoryl)benzenamine | 1197953-47-1 | 169.16 | 50 G
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2-(DiMethylphosphoryl)benzenamine is a chemical compound that serves as a drug intermediate for the synthesis of various active compounds.
- High purity of 99.85%
- Appearance as a solid
- Color ranges from off-white to light yellow
- Molecular formula C8H12NOP
- Recommended storage at 4°C, protected from light
- For solutions, store at -80°C for 6 months or -20°C for 1 month, protected from light
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Cayman Chemical ANTIBODY ML-098 1mg
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An activator of the GTP-binding protein Rab7 (EC50 = 77.6 nM) that demonstrates selectivity against the related GTPases cdc42, Ras, Rab-2A, and Rac1 (EC50s = 588.8, 346.7, 158.5, and 794.3 nM, respectively)
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Abcam U0126, Selective MKK inhibitor, 1MG
MW 380.5 Da, Purity >98%. Selective non-competitive inhibitor of MAP kinase kinase (MKK). Inhibits MKK1, MKK2 (IC₅₀ values of 0.07 and 0.06 μM, respectively) and MKK5 with little or no effect on a wide range of other kinases. Centrally active following systemic administration in vivo.
The product is subject to the following: Abcam Restricted Use Statement
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Medchemexpress LLC HY-12661A 10mg , AMG PERK 44 CAS:1883548-84-2 Purity:>98%
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HY-12661A 10mg AMG PERK 44 CAS: 1883548-84-2 AMG PERK 44 is an orally active and highly selective PERK inhibitor with an IC50 of 6 nM. AMG PERK 44 has 1000-fold and 160-fold selectivity over GCN2 (IC50=7300 nM) and B-Raf (IC50 >1000 nM), respectively. AMG PERK 44 induces autophagy. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Cayman Chemical 6R5 6 7 8tetrahydroLBIo 5mg
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A cofactor for production of aromatic amino acids, neurotransmitters, and nitric oxide
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Cell Signaling Technology FastScantm Phospho-Akt Thr308 ELISA Kit 5 Kit
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FastScantm Phospho-Akt Thr308 ELISA Kit 5 Kit
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Selleck Chemical LLC Omadacycline hydrochloride E4983-100MG
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Omadacycline hydrochloride (PTK0796 hydrochloride) is a first-in-class orally active member of the tetracycline class of antibiotics Omadacycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit Omadacycline hydrochloride exhibits broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria as well as atypical bacteria
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Medchemexpress LLC Srt3109 | 1204707-71-0 | C18H23F2N5O4S2 | 100 MG
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SRT3109 is an antagonist of CXCR2, with a pIC50 of 8.2, and is utilized in the research of chemokine-mediated diseases. It is intended for research use only and is not sold to patients. The product appears as a solid with a white to off-white color and has a molecular weight of 475.53 and a purity of 99.68%.
- Antagonist of CXCR2
- Used in research of chemokine mediated diseases
- Appears as a white to off-white solid
- High purity of 99.68%
- Molecular weight of 475.53
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Sigma Aldrich Fine Chemicals Biosciences PF-04531083 >=98% (HPLC) | 1079400-07-9 | 5MG
PF-04531083 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 357.79 | 1079400-07-9 | 5MG
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Medchemexpress LLC BMS-593214 1mg | 1004551-40-9 | 505.56 | C31H27N3O4 | 1 MG
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This compound is an active site-directed Factor VIIa (FVIIa) inhibitor with antithrombotic and antihaemostatic activity for preclinical research use. It inhibits human FVIIa and modulates the VIIa-activated substrate FX; in vivo studies show prevention of carotid artery and vena cava thrombosis. Supplied as a solid and as DMSO solutions; consult the datasheet for storage and handling.
- High purity suitable for research applications.
- Direct competitive inhibitor of human FVIIa.
- Demonstrated antithrombotic activity in animal models.
- Soluble in DMSO at high concentration; ultrasonic treatment may be required.
- Available as solid quantities and as ready-to-use DMSO solutions.
- Store powder and solutions at recommended temperatures to preserve stability.
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Medchemexpress LLC β-Hydroxypropiovanillone | 2196-18-1 | 5 MG
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β-Hydroxypropiovanillone, a natural compound, shows significant concentration-dependent inhibitory effects on α-glucosidase with an IC50 of 257.8 μg/mL. It is for research use only and not sold to patients.
- Natural compound
- Inhibitory effects on α-glucosidase with an IC50 of 257.8 μg/mL
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Apexbio Technology LLC Tubastatin A, 50mg. Cas: 1252003-15-8 MFCD: MFCD18071463. HDAC6 inhibitor,potent and selective
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Tubastatin A is a potent and selective inhibitor of HDAC6 with IC50 value of 15 nM [1]. Histone deacetylases (HDACs) and histone acetyltransferases (HATs) mediates the balance between histone deacetylation and acetylation. Other sizes are available. Please inqury us for quote.
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Medchemexpress LLC TAE-1 10mg | 1414469-59-2 | 1128.57 | C39H51I3N6O9 | 10 MG
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TAE-1 is a small-molecule research compound that potently inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) and reduces amyloid-β (Aβ) fibril formation and aggregation, making it useful for in vitro and preclinical studies related to Alzheimer's disease.
- High potency against AChE and BuChE.
- Inhibits amyloid-β fibril formation and aggregation.
- Supplied as a solid with reported purity of 96.17%.
- Soluble in DMSO at 125 mg/mL (110.76 mM) with ultrasonic warming and heating to 60°C recommended.
- Stable under recommended storage conditions for research use.
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